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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

72 years

Body Mass Index

20.69

2.Nutritional status

albumin

32 g/L

preaalbumin

192 mg/L

transferrin

1.3 g/L

3.liver function

Alanine aminotransferase

22 U/L

Total bilirubin

12 mmol/L

4.immunologic function

CD3

32.6 %

CD4

25.2 %

CD8

12.1 %

CD4/CD8

2.15

IgA

1.94 %

IgG

8.75 %

IgM

0.47 %

5.Inflammatory markers

C-reactive protein

5 mg/L

Interleukin 6

2.2 pg/L

3.pre-operation
1.Nutritional status

albumin

32 g/L

preaalbumin

240 mg/L

transferrin

1.41 g/L

2.liver function

alanine aminotransferase

12 U/L

Total bilirubin

13 mmol/L

3.immunologic function

CD3

62.5 %

CD4

33 %

CD8

24.8 %

CD4/CD8

1.32

IgA

1.07 g/L

IgG

6.2 g/L

IgM

0.47 g/L

4.Inflammatory markers

C-reactive protein

5.7 mg/L

Interleukin 6

2.5 pg/L

4.three days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

265 mg/L

transferrin

1.76 g/L

2.liver function

Alanine aminotransferase

78 U/L

Total bilirubin

9 mmol/L

3.immunologic function

CD3

41.8 %

CD4

27.8 %

CD8

16.2 %

CD4/CD8

1.66

IgA

0.67 g/L

IgG

7.69 g/L

IgM

0.81 g/L

4.Inflammatory markers

C-reactive protein

7 mg/L

Interleukin 6

21.4 pg/L

5.seven days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

271 mg/L

transferrin

1.88 g/L

2.liver function

Alanine aminotransferase

63 U/L

Total bilirubin

36 mmol/L

3.immunologic function

CD3

54.9 %

CD4

29.9 %

CD8

21.4 %

CD4/CD8

1.16

IgA

0.97 g/L

IgG

10.5 g/L

IgM

0.66 g/L

4.Inflammatory markers

C-reactive protein

16 mg/L

Interleukin 6

9.3 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

52587 yuan

hospital stays

22 Day