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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

83 years

Body Mass Index

19.27

2.Nutritional status

albumin

32 g/L

preaalbumin

198 mg/L

transferrin

2.3 g/L

3.liver function

Alanine aminotransferase

12 U/L

Total bilirubin

15 mmol/L

4.immunologic function

CD3

26.6 %

CD4

28.7 %

CD8

18.1 %

CD4/CD8

1.58

IgA

0.78 %

IgG

5.1 %

IgM

0.47 %

5.Inflammatory markers

C-reactive protein

6.8 mg/L

Interleukin 6

1.5 pg/L

3.pre-operation
1.Nutritional status

albumin

30 g/L

preaalbumin

200 mg/L

transferrin

1.69 g/L

2.liver function

alanine aminotransferase

21 U/L

Total bilirubin

15 mmol/L

3.immunologic function

CD3

36.1 %

CD4

30.2 %

CD8

21.6 %

CD4/CD8

1.35

IgA

0.32 g/L

IgG

9.3 g/L

IgM

0.88 g/L

4.Inflammatory markers

C-reactive protein

5 mg/L

Interleukin 6

3.9 pg/L

4.three days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

197 mg/L

transferrin

2.15 g/L

2.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

26 mmol/L

3.immunologic function

CD3

28.1 %

CD4

29.3 %

CD8

27.2 %

CD4/CD8

1.05

IgA

0.73 g/L

IgG

5.7 g/L

IgM

1.98 g/L

4.Inflammatory markers

C-reactive protein

22 mg/L

Interleukin 6

6.8 pg/L

5.seven days after surgery
1.Nutritional status

albumin

30 g/L

preaalbumin

201 mg/L

transferrin

1.58 g/L

2.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

26 mmol/L

3.immunologic function

CD3

43.1 %

CD4

30.8 %

CD8

22.3 %

CD4/CD8

1.32

IgA

1.06 g/L

IgG

12.5 g/L

IgM

1.12 g/L

4.Inflammatory markers

C-reactive protein

21 mg/L

Interleukin 6

7.6 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

61031 yuan

hospital stays

22 Day