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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

69 years

Body Mass Index

18.18

2.Nutritional status

albumin

36 g/L

preaalbumin

220 mg/L

transferrin

1.06 g/L

3.liver function

Alanine aminotransferase

9 U/L

Total bilirubin

13 mmol/L

4.immunologic function

CD3

58.2 %

CD4

39.8 %

CD8

14.4 %

CD4/CD8

2.25

IgA

1.14 %

IgG

9.8 %

IgM

1.37 %

5.Inflammatory markers

C-reactive protein

12.5 mg/L

Interleukin 6

3.5 pg/L

3.pre-operation
1.Nutritional status

albumin

29 g/L

preaalbumin

20 mg/L

transferrin

1.8 g/L

2.liver function

alanine aminotransferase

27 U/L

Total bilirubin

9 mmol/L

3.immunologic function

CD3

56.2 %

CD4

47.7 %

CD8

22.8 %

CD4/CD8

1.84

IgA

1.89 g/L

IgG

6.9 g/L

IgM

1.27 g/L

4.Inflammatory markers

C-reactive protein

8 mg/L

Interleukin 6

3.8 pg/L

4.three days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

219 mg/L

transferrin

1.38 g/L

2.liver function

Alanine aminotransferase

29 U/L

Total bilirubin

35 mmol/L

3.immunologic function

CD3

43.1 %

CD4

30.8 %

CD8

22.3 %

CD4/CD8

1.28

IgA

0.86 g/L

IgG

7.6 g/L

IgM

0.77 g/L

4.Inflammatory markers

C-reactive protein

28 mg/L

Interleukin 6

7.6 pg/L

5.seven days after surgery
1.Nutritional status

albumin

37 g/L

preaalbumin

261 mg/L

transferrin

2.12 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

19 mmol/L

3.immunologic function

CD3

52.2 %

CD4

49.3 %

CD8

20.9 %

CD4/CD8

2.37

IgA

1.77 g/L

IgG

8.6 g/L

IgM

1.22 g/L

4.Inflammatory markers

C-reactive protein

7 mg/L

Interleukin 6

6.8 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

51880 yuan

hospital stays

21 Day