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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

66 years

Body Mass Index

19.96

2.Nutritional status

albumin

26 g/L

preaalbumin

188 mg/L

transferrin

0.58 g/L

3.liver function

Alanine aminotransferase

24 U/L

Total bilirubin

14 mmol/L

4.immunologic function

CD3

37.4 %

CD4

38.3 %

CD8

22.8 %

CD4/CD8

1.82

IgA

0.32 %

IgG

3.3 %

IgM

1.15 %

5.Inflammatory markers

C-reactive protein

4.6 mg/L

Interleukin 6

3.2 pg/L

3.pre-operation
1.Nutritional status

albumin

35 g/L

preaalbumin

241 mg/L

transferrin

1.36 g/L

2.liver function

alanine aminotransferase

24 U/L

Total bilirubin

14 mmol/L

3.immunologic function

CD3

46.4 %

CD4

35.8 %

CD8

17.5 %

CD4/CD8

1.5

IgA

1.98 g/L

IgG

6.5 g/L

IgM

1.47 g/L

4.Inflammatory markers

C-reactive protein

4 mg/L

Interleukin 6

2.8 pg/L

4.three days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

236 mg/L

transferrin

2.12 g/L

2.liver function

Alanine aminotransferase

17 U/L

Total bilirubin

27 mmol/L

3.immunologic function

CD3

52.8 %

CD4

34.2 %

CD8

12.4 %

CD4/CD8

1.42

IgA

1.26 g/L

IgG

6.5 g/L

IgM

0.58 g/L

4.Inflammatory markers

C-reactive protein

14 mg/L

Interleukin 6

23.3 pg/L

5.seven days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

268 mg/L

transferrin

2.41 g/L

2.liver function

Alanine aminotransferase

32 U/L

Total bilirubin

23 mmol/L

3.immunologic function

CD3

53.5 %

CD4

35.6 %

CD8

24.8 %

CD4/CD8

1.55

IgA

0.85 g/L

IgG

8.8 g/L

IgM

1.6 g/L

4.Inflammatory markers

C-reactive protein

4.1 mg/L

Interleukin 6

2.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

57892 yuan

hospital stays

20 Day