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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

67 years

Body Mass Index

20.86

2.Nutritional status

albumin

35 g/L

preaalbumin

252 mg/L

transferrin

2.21 g/L

3.liver function

Alanine aminotransferase

32 U/L

Total bilirubin

15 mmol/L

4.immunologic function

CD3

46.2 %

CD4

23.3 %

CD8

26.5 %

CD4/CD8

0.89

IgA

1.26 %

IgG

9.6 %

IgM

0.98 %

5.Inflammatory markers

C-reactive protein

5.2 mg/L

Interleukin 6

6.7 pg/L

3.pre-operation
1.Nutritional status

albumin

36 g/L

preaalbumin

244 mg/L

transferrin

2.26 g/L

2.liver function

alanine aminotransferase

22 U/L

Total bilirubin

23 mmol/L

3.immunologic function

CD3

45.1 %

CD4

23.3 %

CD8

24.5 %

CD4/CD8

0.97

IgA

0.93 g/L

IgG

4.7 g/L

IgM

0.98 g/L

4.Inflammatory markers

C-reactive protein

2.8 mg/L

Interleukin 6

2.2 pg/L

4.three days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

226 mg/L

transferrin

1.83 g/L

2.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

60 mmol/L

3.immunologic function

CD3

42.8 %

CD4

27 %

CD8

29.3 %

CD4/CD8

0.89

IgA

0.37 g/L

IgG

9.38 g/L

IgM

1.82 g/L

4.Inflammatory markers

C-reactive protein

15 mg/L

Interleukin 6

7.5 pg/L

5.seven days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

276 mg/L

transferrin

2.13 g/L

2.liver function

Alanine aminotransferase

18 U/L

Total bilirubin

42 mmol/L

3.immunologic function

CD3

49.7 %

CD4

19.6 %

CD8

21.9 %

CD4/CD8

0.77

IgA

0.82 g/L

IgG

3.38 g/L

IgM

0.37 g/L

4.Inflammatory markers

C-reactive protein

17 mg/L

Interleukin 6

21.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

49031 yuan

hospital stays

19 Day