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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

76 years

Body Mass Index

22.58

2.Nutritional status

albumin

38 g/L

preaalbumin

250 mg/L

transferrin

2.39 g/L

3.liver function

Alanine aminotransferase

16 U/L

Total bilirubin

10 mmol/L

4.immunologic function

CD3

58.4 %

CD4

28.8 %

CD8

21.7 %

CD4/CD8

1.28

IgA

0.56 %

IgG

8.24 %

IgM

1.47 %

5.Inflammatory markers

C-reactive protein

2.6 mg/L

Interleukin 6

2 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

188 mg/L

transferrin

1.06 g/L

2.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

9 mmol/L

3.immunologic function

CD3

34.1 %

CD4

33.3 %

CD8

18.4 %

CD4/CD8

1.64

IgA

1.2 g/L

IgG

1.85 g/L

IgM

1.15 g/L

4.Inflammatory markers

C-reactive protein

13 mg/L

Interleukin 6

8.4 pg/L

5.seven days after surgery
1.Nutritional status

albumin

35 g/L

preaalbumin

239 mg/L

transferrin

1.38 g/L

2.liver function

Alanine aminotransferase

24 U/L

Total bilirubin

16 mmol/L

3.immunologic function

CD3

36.1 %

CD4

27.8 %

CD8

27.2 %

CD4/CD8

1.02

IgA

1.25 g/L

IgG

7.7 g/L

IgM

0.45 g/L

4.Inflammatory markers

C-reactive protein

10 mg/L

Interleukin 6

23.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

55564 yuan

hospital stays

18 Day