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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

68 years

Body Mass Index

21.41

2.Nutritional status

albumin

30 g/L

preaalbumin

190 mg/L

transferrin

2.08 g/L

3.liver function

Alanine aminotransferase

18 U/L

Total bilirubin

23 mmol/L

4.immunologic function

CD3

58.2 %

CD4

31.7 %

CD8

31.8 %

CD4/CD8

0.83

IgA

1.43 %

IgG

4.3 %

IgM

0.56 %

5.Inflammatory markers

C-reactive protein

3 mg/L

Interleukin 6

6.4 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

25 g/L

preaalbumin

173 mg/L

transferrin

1.78 g/L

2.liver function

Alanine aminotransferase

19 U/L

Total bilirubin

11 mmol/L

3.immunologic function

CD3

42.9 %

CD4

34.8 %

CD8

21.7 %

CD4/CD8

1.42

IgA

0.36 g/L

IgG

2.56 g/L

IgM

0.24 g/L

4.Inflammatory markers

C-reactive protein

4 mg/L

Interleukin 6

6.4 pg/L

5.seven days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

213 mg/L

transferrin

1.92 g/L

2.liver function

Alanine aminotransferase

32 U/L

Total bilirubin

20 mmol/L

3.immunologic function

CD3

49.9 %

CD4

31 %

CD8

19.4 %

CD4/CD8

1.34

IgA

1.07 g/L

IgG

5.7 g/L

IgM

0.41 g/L

4.Inflammatory markers

C-reactive protein

11 mg/L

Interleukin 6

8.1 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

48615 yuan

hospital stays

19 Day