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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

72 years

Body Mass Index

18.38

2.Nutritional status

albumin

28 g/L

preaalbumin

165 mg/L

transferrin

1.92 g/L

3.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

15 mmol/L

4.immunologic function

CD3

32.9 %

CD4

19.3 %

CD8

17.4 %

CD4/CD8

1.24

IgA

1.85 %

IgG

9.8 %

IgM

0.9 %

5.Inflammatory markers

C-reactive protein

6.3 mg/L

Interleukin 6

1.4 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

24 g/L

preaalbumin

188 mg/L

transferrin

1.48 g/L

2.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

12 mmol/L

3.immunologic function

CD3

57.2 %

CD4

40.7 %

CD8

23.8 %

CD4/CD8

1.76

IgA

1.1 g/L

IgG

5.43 g/L

IgM

0.3 g/L

4.Inflammatory markers

C-reactive protein

23 mg/L

Interleukin 6

22 pg/L

5.seven days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

228 mg/L

transferrin

1.65 g/L

2.liver function

Alanine aminotransferase

76 U/L

Total bilirubin

12 mmol/L

3.immunologic function

CD3

38.9 %

CD4

27.8 %

CD8

25.3 %

CD4/CD8

1.02

IgA

0.5 g/L

IgG

5.6 g/L

IgM

1.16 g/L

4.Inflammatory markers

C-reactive protein

8 mg/L

Interleukin 6

12.9 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

47766 yuan

hospital stays

18 Day