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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

66 years

Body Mass Index

21.22

2.Nutritional status

albumin

32 g/L

preaalbumin

183 mg/L

transferrin

2.36 g/L

3.liver function

Alanine aminotransferase

12 U/L

Total bilirubin

9 mmol/L

4.immunologic function

CD3

51.3 %

CD4

33 %

CD8

25.9 %

CD4/CD8

1.32

IgA

1.89 %

IgG

7 %

IgM

1.27 %

5.Inflammatory markers

C-reactive protein

4.7 mg/L

Interleukin 6

2.5 pg/L

3.pre-operation
1.Nutritional status

albumin

31 g/L

preaalbumin

233 mg/L

transferrin

2.14 g/L

2.liver function

alanine aminotransferase

24 U/L

Total bilirubin

11 mmol/L

3.immunologic function

CD3

48.5 %

CD4

31.7 %

CD8

23.8 %

CD4/CD8

1.23

IgA

2.26 g/L

IgG

9.4 g/L

IgM

0.77 g/L

4.Inflammatory markers

C-reactive protein

3.2 mg/L

Interleukin 6

2.4 pg/L

4.three days after surgery
1.Nutritional status

albumin

31 g/L

preaalbumin

264 mg/L

transferrin

2.55 g/L

2.liver function

Alanine aminotransferase

82 U/L

Total bilirubin

13 mmol/L

3.immunologic function

CD3

45 %

CD4

21.8 %

CD8

16.8 %

CD4/CD8

1.34

IgA

0.9 g/L

IgG

7.35 g/L

IgM

0.68 g/L

4.Inflammatory markers

C-reactive protein

15 mg/L

Interleukin 6

21.5 pg/L

5.seven days after surgery
1.Nutritional status

albumin

37 g/L

preaalbumin

272 mg/L

transferrin

1.55 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

36 mmol/L

3.immunologic function

CD3

52.4 %

CD4

39.5 %

CD8

16.8 %

CD4/CD8

2.19

IgA

0.5 g/L

IgG

8.7 g/L

IgM

1.16 g/L

4.Inflammatory markers

C-reactive protein

15 mg/L

Interleukin 6

9.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

54507 yuan

hospital stays

20 Day