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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

75 years

Body Mass Index

21.3

2.Nutritional status

albumin

30 g/L

preaalbumin

180 mg/L

transferrin

2.66 g/L

3.liver function

Alanine aminotransferase

6 U/L

Total bilirubin

16 mmol/L

4.immunologic function

CD3

55.9 %

CD4

37.8 %

CD8

19.2 %

CD4/CD8

1.89

IgA

0.82 %

IgG

8.3 %

IgM

1.13 %

5.Inflammatory markers

C-reactive protein

6.9 mg/L

Interleukin 6

11.7 pg/L

3.pre-operation
1.Nutritional status

albumin

34 g/L

preaalbumin

220 mg/L

transferrin

2.66 g/L

2.liver function

alanine aminotransferase

36 U/L

Total bilirubin

13 mmol/L

3.immunologic function

CD3

58.6 %

CD4

37.8 %

CD8

19.2 %

CD4/CD8

1.47

IgA

1.14 g/L

IgG

8.6 g/L

IgM

0.56 g/L

4.Inflammatory markers

C-reactive protein

3.6 mg/L

Interleukin 6

8.9 pg/L

4.three days after surgery
1.Nutritional status

albumin

39 g/L

preaalbumin

254 mg/L

transferrin

2.33 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

18 mmol/L

3.immunologic function

CD3

51.2 %

CD4

37.7 %

CD8

19.9 %

CD4/CD8

1.58

IgA

1.52 g/L

IgG

7.1 g/L

IgM

0.78 g/L

4.Inflammatory markers

C-reactive protein

90 mg/L

Interleukin 6

54.1 pg/L

5.seven days after surgery
1.Nutritional status

albumin

40 g/L

preaalbumin

253 mg/L

transferrin

1.97 g/L

2.liver function

Alanine aminotransferase

19 U/L

Total bilirubin

18 mmol/L

3.immunologic function

CD3

55.2 %

CD4

37.9 %

CD8

20.6 %

CD4/CD8

1.83

IgA

0.96 g/L

IgG

6.8 g/L

IgM

1.08 g/L

4.Inflammatory markers

C-reactive protein

3.3 mg/L

Interleukin 6

27.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

56690 yuan

hospital stays

21 Day