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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

77 years

Body Mass Index

21.61

2.Nutritional status

albumin

32 g/L

preaalbumin

173 mg/L

transferrin

2.47 g/L

3.liver function

Alanine aminotransferase

19 U/L

Total bilirubin

15 mmol/L

4.immunologic function

CD3

29.8 %

CD4

29.5 %

CD8

21.6 %

CD4/CD8

1.21

IgA

2.03 %

IgG

9.7 %

IgM

0.38 %

5.Inflammatory markers

C-reactive protein

4.3 mg/L

Interleukin 6

2.9 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

29 g/L

preaalbumin

153 mg/L

transferrin

1.6 g/L

2.liver function

Alanine aminotransferase

27 U/L

Total bilirubin

17 mmol/L

3.immunologic function

CD3

37.8 %

CD4

37.7 %

CD8

28.7 %

CD4/CD8

1.42

IgA

1.37 g/L

IgG

3.08 g/L

IgM

1.28 g/L

4.Inflammatory markers

C-reactive protein

88 mg/L

Interleukin 6

62.9 pg/L

5.seven days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

201 mg/L

transferrin

2.21 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

30 mmol/L

3.immunologic function

CD3

36.2 %

CD4

26.6 %

CD8

27.1 %

CD4/CD8

0.99

IgA

0.73 g/L

IgG

8.25 g/L

IgM

0.37 g/L

4.Inflammatory markers

C-reactive protein

33 mg/L

Interleukin 6

11.3 pg/L

6.complications

infection

yes

anastomotic leakage

7.Discharge summary

hospitalization costs

64628 yuan

hospital stays

24 Day