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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

68 years

Body Mass Index

21.16

2.Nutritional status

albumin

32 g/L

preaalbumin

163 mg/L

transferrin

1.85 g/L

3.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

17 mmol/L

4.immunologic function

CD3

36.1 %

CD4

35.3 %

CD8

14.4 %

CD4/CD8

2.24

IgA

1.85 %

IgG

3.85 %

IgM

1.02 %

5.Inflammatory markers

C-reactive protein

8.2 mg/L

Interleukin 6

4.8 pg/L

3.pre-operation
1.Nutritional status

albumin

40 g/L

preaalbumin

233 mg/L

transferrin

2.21 g/L

2.liver function

alanine aminotransferase

26 U/L

Total bilirubin

17 mmol/L

3.immunologic function

CD3

51.8 %

CD4

37.6 %

CD8

18.3 %

CD4/CD8

2.18

IgA

1.38 g/L

IgG

5.13 g/L

IgM

0.55 g/L

4.Inflammatory markers

C-reactive protein

3.2 mg/L

Interleukin 6

6.2 pg/L

4.three days after surgery
1.Nutritional status

albumin

35 g/L

preaalbumin

282 mg/L

transferrin

2.45 g/L

2.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

27 mmol/L

3.immunologic function

CD3

48.3 %

CD4

36.2 %

CD8

20.8 %

CD4/CD8

1.62

IgA

1.31 g/L

IgG

5.3 g/L

IgM

1.66 g/L

4.Inflammatory markers

C-reactive protein

12 mg/L

Interleukin 6

7.3 pg/L

5.seven days after surgery
1.Nutritional status

albumin

39 g/L

preaalbumin

283 mg/L

transferrin

2.03 g/L

2.liver function

Alanine aminotransferase

33 U/L

Total bilirubin

20 mmol/L

3.immunologic function

CD3

59.6 %

CD4

40.2 %

CD8

21.5 %

CD4/CD8

2.06

IgA

1.36 g/L

IgG

13.9 g/L

IgM

0.96 g/L

4.Inflammatory markers

C-reactive protein

5.5 mg/L

Interleukin 6

6.2 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

53763 yuan

hospital stays

20 Day