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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

66 years

Body Mass Index

17.51

2.Nutritional status

albumin

28 g/L

preaalbumin

152 mg/L

transferrin

1.63 g/L

3.liver function

Alanine aminotransferase

18 U/L

Total bilirubin

8 mmol/L

4.immunologic function

CD3

51.2 %

CD4

38.1 %

CD8

26.8 %

CD4/CD8

1.31

IgA

1.08 %

IgG

7.3 %

IgM

0.78 %

5.Inflammatory markers

C-reactive protein

2.4 mg/L

Interleukin 6

9 pg/L

3.pre-operation
1.Nutritional status

albumin

33 g/L

preaalbumin

199 mg/L

transferrin

1.85 g/L

2.liver function

alanine aminotransferase

22 U/L

Total bilirubin

8 mmol/L

3.immunologic function

CD3

51.2 %

CD4

26.6 %

CD8

22.6 %

CD4/CD8

0.99

IgA

1.08 g/L

IgG

4.3 g/L

IgM

1.05 g/L

4.Inflammatory markers

C-reactive protein

6 mg/L

Interleukin 6

9.2 pg/L

4.three days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

233 mg/L

transferrin

1.78 g/L

2.liver function

Alanine aminotransferase

27 U/L

Total bilirubin

14 mmol/L

3.immunologic function

CD3

46.5 %

CD4

33.2 %

CD8

24.6 %

CD4/CD8

1.34

IgA

1.1 g/L

IgG

2.9 g/L

IgM

0.29 g/L

4.Inflammatory markers

C-reactive protein

37 mg/L

Interleukin 6

23.6 pg/L

5.seven days after surgery
1.Nutritional status

albumin

26 g/L

preaalbumin

266 mg/L

transferrin

1.9 g/L

2.liver function

Alanine aminotransferase

25 U/L

Total bilirubin

21 mmol/L

3.immunologic function

CD3

50.3 %

CD4

29.7 %

CD8

20.5 %

CD4/CD8

1.37

IgA

1.62 g/L

IgG

11.5 g/L

IgM

1.06 g/L

4.Inflammatory markers

C-reactive protein

7.7 mg/L

Interleukin 6

9.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

65443 yuan

hospital stays

19 Day