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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

67 years

Body Mass Index

21.01

2.Nutritional status

albumin

38 g/L

preaalbumin

162 mg/L

transferrin

2.16 g/L

3.liver function

Alanine aminotransferase

17 U/L

Total bilirubin

13 mmol/L

4.immunologic function

CD3

47.9 %

CD4

32.7 %

CD8

18.9 %

CD4/CD8

1.68

IgA

0.66 %

IgG

10.6 %

IgM

1.2 %

5.Inflammatory markers

C-reactive protein

3 mg/L

Interleukin 6

4.7 pg/L

3.pre-operation
1.Nutritional status

albumin

29 g/L

preaalbumin

247 mg/L

transferrin

2.21 g/L

2.liver function

alanine aminotransferase

28 U/L

Total bilirubin

19 mmol/L

3.immunologic function

CD3

42.1 %

CD4

41.8 %

CD8

16.2 %

CD4/CD8

2.24

IgA

1.36 g/L

IgG

7.7 g/L

IgM

0.97 g/L

4.Inflammatory markers

C-reactive protein

8 mg/L

Interleukin 6

9.1 pg/L

4.three days after surgery
1.Nutritional status

albumin

29 g/L

preaalbumin

268 mg/L

transferrin

1.76 g/L

2.liver function

Alanine aminotransferase

23 U/L

Total bilirubin

39 mmol/L

3.immunologic function

CD3

43.5 %

CD4

20.9 %

CD8

13.8 %

CD4/CD8

1.37

IgA

0.24 g/L

IgG

7.83 g/L

IgM

1.58 g/L

4.Inflammatory markers

C-reactive protein

17 mg/L

Interleukin 6

9.5 pg/L

5.seven days after surgery
1.Nutritional status

albumin

35 g/L

preaalbumin

268 mg/L

transferrin

1.76 g/L

2.liver function

Alanine aminotransferase

14 U/L

Total bilirubin

60 mmol/L

3.immunologic function

CD3

59.6 %

CD4

30.9 %

CD8

14.8 %

CD4/CD8

2.28

IgA

1.18 g/L

IgG

7.2 g/L

IgM

2.04 g/L

4.Inflammatory markers

C-reactive protein

21 mg/L

Interleukin 6

15.2 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

52032 yuan

hospital stays

19 Day