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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

68 years

Body Mass Index

15.5

2.Nutritional status

albumin

26 g/L

preaalbumin

161 mg/L

transferrin

1.88 g/L

3.liver function

Alanine aminotransferase

18 U/L

Total bilirubin

10 mmol/L

4.immunologic function

CD3

32.9 %

CD4

19.3 %

CD8

12.4 %

CD4/CD8

1.54

IgA

0.72 %

IgG

4.3 %

IgM

0.9 %

5.Inflammatory markers

C-reactive protein

4.7 mg/L

Interleukin 6

5.3 pg/L

3.pre-operation
1.Nutritional status

albumin

27 g/L

preaalbumin

199 mg/L

transferrin

1.73 g/L

2.liver function

alanine aminotransferase

33 U/L

Total bilirubin

12 mmol/L

3.immunologic function

CD3

34.5 %

CD4

19.3 %

CD8

22.4 %

CD4/CD8

0.84

IgA

0.5 g/L

IgG

6.5 g/L

IgM

0.16 g/L

4.Inflammatory markers

C-reactive protein

2.7 mg/L

Interleukin 6

4.5 pg/L

4.three days after surgery
1.Nutritional status

albumin

27 g/L

preaalbumin

198 mg/L

transferrin

1.38 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

17 mmol/L

3.immunologic function

CD3

37.4 %

CD4

29.9 %

CD8

21.4 %

CD4/CD8

1.26

IgA

0.86 g/L

IgG

5.15 g/L

IgM

0.97 g/L

4.Inflammatory markers

C-reactive protein

16 mg/L

Interleukin 6

21.3 pg/L

5.seven days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

201 mg/L

transferrin

1.38 g/L

2.liver function

Alanine aminotransferase

25 U/L

Total bilirubin

40 mmol/L

3.immunologic function

CD3

38.2 %

CD4

36.1 %

CD8

26.2 %

CD4/CD8

1.1

IgA

0.81 g/L

IgG

7.69 g/L

IgM

0.77 g/L

4.Inflammatory markers

C-reactive protein

7 mg/L

Interleukin 6

6.4 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

54768 yuan

hospital stays

19 Day