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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

75 years

Body Mass Index

21.01

2.Nutritional status

albumin

37 g/L

preaalbumin

185 mg/L

transferrin

1.54 g/L

3.liver function

Alanine aminotransferase

31 U/L

Total bilirubin

10 mmol/L

4.immunologic function

CD3

46.4 %

CD4

31.4 %

CD8

31.7 %

CD4/CD8

0.88

IgA

0.56 %

IgG

8.24 %

IgM

0.36 %

5.Inflammatory markers

C-reactive protein

6.8 mg/L

Interleukin 6

2.6 pg/L

3.pre-operation
1.Nutritional status

albumin

35 g/L

preaalbumin

212 mg/L

transferrin

1.76 g/L

2.liver function

alanine aminotransferase

31 U/L

Total bilirubin

10 mmol/L

3.immunologic function

CD3

49.5 %

CD4

28.2 %

CD8

20.1 %

CD4/CD8

1.45

IgA

0.55 g/L

IgG

2.75 g/L

IgM

0.36 g/L

4.Inflammatory markers

C-reactive protein

2.8 mg/L

Interleukin 6

2.6 pg/L

4.three days after surgery
1.Nutritional status

albumin

36 g/L

preaalbumin

247 mg/L

transferrin

1.91 g/L

2.liver function

Alanine aminotransferase

22 U/L

Total bilirubin

16 mmol/L

3.immunologic function

CD3

55.6 %

CD4

32.1 %

CD8

22.6 %

CD4/CD8

1.41

IgA

1.26 g/L

IgG

3.1 g/L

IgM

0.64 g/L

4.Inflammatory markers

C-reactive protein

8 mg/L

Interleukin 6

16.2 pg/L

5.seven days after surgery
1.Nutritional status

albumin

38 g/L

preaalbumin

276 mg/L

transferrin

2.22 g/L

2.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

9 mmol/L

3.immunologic function

CD3

48.5 %

CD4

37.8 %

CD8

15.8 %

CD4/CD8

2.14

IgA

1.28 g/L

IgG

9.8 g/L

IgM

1.26 g/L

4.Inflammatory markers

C-reactive protein

24 mg/L

Interleukin 6

17.3 pg/L

6.complications

infection

yes

anastomotic leakage

7.Discharge summary

hospitalization costs

71384 yuan

hospital stays

20 Day