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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

66 years

Body Mass Index

16.85

2.Nutritional status

albumin

27 g/L

preaalbumin

188 mg/L

transferrin

1.69 g/L

3.liver function

Alanine aminotransferase

24 U/L

Total bilirubin

8 mmol/L

4.immunologic function

CD3

37.4 %

CD4

21.1 %

CD8

20.8 %

CD4/CD8

1.02

IgA

1.85 %

IgG

13.3 %

IgM

1.05 %

5.Inflammatory markers

C-reactive protein

2 mg/L

Interleukin 6

3.4 pg/L

3.pre-operation
1.Nutritional status

albumin

31 g/L

preaalbumin

203 mg/L

transferrin

1.83 g/L

2.liver function

alanine aminotransferase

25 U/L

Total bilirubin

10 mmol/L

3.immunologic function

CD3

45.8 %

CD4

31 %

CD8

25.9 %

CD4/CD8

1.32

IgA

1.25 g/L

IgG

9.3 g/L

IgM

0.36 g/L

4.Inflammatory markers

C-reactive protein

6.2 mg/L

Interleukin 6

8.1 pg/L

4.three days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

235 mg/L

transferrin

1.98 g/L

2.liver function

Alanine aminotransferase

17 U/L

Total bilirubin

16 mmol/L

3.immunologic function

CD3

28.4 %

CD4

18.6 %

CD8

18.4 %

CD4/CD8

1.02

IgA

0.36 g/L

IgG

9.51 g/L

IgM

0.5 g/L

4.Inflammatory markers

C-reactive protein

17 mg/L

Interleukin 6

18.3 pg/L

5.seven days after surgery
1.Nutritional status

albumin

35 g/L

preaalbumin

265 mg/L

transferrin

2.18 g/L

2.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

28 mmol/L

3.immunologic function

CD3

55.9 %

CD4

38.6 %

CD8

18.4 %

CD4/CD8

2.13

IgA

1.27 g/L

IgG

9.3 g/L

IgM

0.67 g/L

4.Inflammatory markers

C-reactive protein

37 mg/L

Interleukin 6

32.3 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

21902 yuan

hospital stays

19 Day