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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

66 years

Body Mass Index

20.4

2.Nutritional status

albumin

27 g/L

preaalbumin

238 mg/L

transferrin

1.79 g/L

3.liver function

Alanine aminotransferase

22 U/L

Total bilirubin

16 mmol/L

4.immunologic function

CD3

63.9 %

CD4

37.7 %

CD8

27.7 %

CD4/CD8

1.24

IgA

1.08 %

IgG

6.5 %

IgM

0.55 %

5.Inflammatory markers

C-reactive protein

12 mg/L

Interleukin 6

3.3 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

33 g/L

preaalbumin

218 mg/L

transferrin

1.32 g/L

2.liver function

Alanine aminotransferase

22 U/L

Total bilirubin

9 mmol/L

3.immunologic function

CD3

57.4 %

CD4

38.5 %

CD8

18.6 %

CD4/CD8

2.06

IgA

1.08 g/L

IgG

2.03 g/L

IgM

0.7 g/L

4.Inflammatory markers

C-reactive protein

90 mg/L

Interleukin 6

71.3 pg/L

5.seven days after surgery
1.Nutritional status

albumin

29 g/L

preaalbumin

199 mg/L

transferrin

1.55 g/L

2.liver function

Alanine aminotransferase

40 U/L

Total bilirubin

29 mmol/L

3.immunologic function

CD3

48.1 %

CD4

23.2 %

CD8

28 %

CD4/CD8

0.75

IgA

0.14 g/L

IgG

7.3 g/L

IgM

0.57 g/L

4.Inflammatory markers

C-reactive protein

5 mg/L

Interleukin 6

17.1 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

42638 yuan

hospital stays

15 Day