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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

70 years

Body Mass Index

21.08

2.Nutritional status

albumin

31 g/L

preaalbumin

140 mg/L

transferrin

2.5 g/L

3.liver function

Alanine aminotransferase

25 U/L

Total bilirubin

11 mmol/L

4.immunologic function

CD3

61.3 %

CD4

29.5 %

CD8

15.8 %

CD4/CD8

1.38

IgA

0.55 %

IgG

1.85 %

IgM

0.9 %

5.Inflammatory markers

C-reactive protein

3.8 mg/L

Interleukin 6

1.6 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

24 g/L

preaalbumin

180 mg/L

transferrin

1.52 g/L

2.liver function

Alanine aminotransferase

13 U/L

Total bilirubin

16 mmol/L

3.immunologic function

CD3

32.3 %

CD4

35.5 %

CD8

18.8 %

CD4/CD8

1.87

IgA

0.29 g/L

IgG

2.55 g/L

IgM

1.31 g/L

4.Inflammatory markers

C-reactive protein

26 mg/L

Interleukin 6

9.6 pg/L

5.seven days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

216 mg/L

transferrin

1.46 g/L

2.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

34 mmol/L

3.immunologic function

CD3

32.7 %

CD4

24.8 %

CD8

19.2 %

CD4/CD8

1.26

IgA

1.45 g/L

IgG

14.5 g/L

IgM

1.47 g/L

4.Inflammatory markers

C-reactive protein

11 mg/L

Interleukin 6

13.9 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

50321 yuan

hospital stays

17 Day