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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

77 years

Body Mass Index

20.48

2.Nutritional status

albumin

35 g/L

preaalbumin

147 mg/L

transferrin

1.82 g/L

3.liver function

Alanine aminotransferase

20 U/L

Total bilirubin

11 mmol/L

4.immunologic function

CD3

57.9 %

CD4

35 %

CD8

19.6 %

CD4/CD8

1.77

IgA

2.33 %

IgG

4.7 %

IgM

1.08 %

5.Inflammatory markers

C-reactive protein

6 mg/L

Interleukin 6

3.7 pg/L

3.pre-operation
1.Nutritional status

albumin

38 g/L

preaalbumin

247 mg/L

transferrin

1.92 g/L

2.liver function

alanine aminotransferase

22 U/L

Total bilirubin

11 mmol/L

3.immunologic function

CD3

69.7 %

CD4

39.3 %

CD8

19.4 %

CD4/CD8

1.86

IgA

2.32 g/L

IgG

5.6 g/L

IgM

1.08 g/L

4.Inflammatory markers

C-reactive protein

6.3 mg/L

Interleukin 6

3.7 pg/L

4.three days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

255 mg/L

transferrin

1.96 g/L

2.liver function

Alanine aminotransferase

12 U/L

Total bilirubin

23 mmol/L

3.immunologic function

CD3

58.3 %

CD4

33.8 %

CD8

23 %

CD4/CD8

1.58

IgA

1.52 g/L

IgG

8.6 g/L

IgM

0.83 g/L

4.Inflammatory markers

C-reactive protein

20 mg/L

Interleukin 6

13.4 pg/L

5.seven days after surgery
1.Nutritional status

albumin

32 g/L

preaalbumin

198 mg/L

transferrin

1.82 g/L

2.liver function

Alanine aminotransferase

29 U/L

Total bilirubin

13 mmol/L

3.immunologic function

CD3

39.7 %

CD4

36.5 %

CD8

18.1 %

CD4/CD8

1.7

IgA

1.74 g/L

IgG

10.6 g/L

IgM

1.33 g/L

4.Inflammatory markers

C-reactive protein

3.8 mg/L

Interleukin 6

11.7 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

60382 yuan

hospital stays

18 Day