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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

70 years

Body Mass Index

16.23

2.Nutritional status

albumin

27 g/L

preaalbumin

208 mg/L

transferrin

1.48 g/L

3.liver function

Alanine aminotransferase

21 U/L

Total bilirubin

12 mmol/L

4.immunologic function

CD3

58.2 %

CD4

36.8 %

CD8

15.2 %

CD4/CD8

2.14

IgA

2.12 %

IgG

10.3 %

IgM

1.13 %

5.Inflammatory markers

C-reactive protein

6 mg/L

Interleukin 6

8.8 pg/L

3.pre-operation
1.Nutritional status

albumin

30 g/L

preaalbumin

229 mg/L

transferrin

1.93 g/L

2.liver function

alanine aminotransferase

29 U/L

Total bilirubin

14 mmol/L

3.immunologic function

CD3

34.6 %

CD4

28.5 %

CD8

20.9 %

CD4/CD8

1.21

IgA

1.3 g/L

IgG

9.6 g/L

IgM

0.67 g/L

4.Inflammatory markers

C-reactive protein

4.6 mg/L

Interleukin 6

8.5 pg/L

4.three days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

263 mg/L

transferrin

1.88 g/L

2.liver function

Alanine aminotransferase

17 U/L

Total bilirubin

22 mmol/L

3.immunologic function

CD3

57.9 %

CD4

37.8 %

CD8

21.6 %

CD4/CD8

1.87

IgA

0.95 g/L

IgG

7.83 g/L

IgM

1.15 g/L

4.Inflammatory markers

C-reactive protein

14 mg/L

Interleukin 6

17 pg/L

5.seven days after surgery
1.Nutritional status

albumin

36 g/L

preaalbumin

263 mg/L

transferrin

1.45 g/L

2.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

14 mmol/L

3.immunologic function

CD3

57.1 %

CD4

24.8 %

CD8

21.6 %

CD4/CD8

1.12

IgA

0.55 g/L

IgG

7.7 g/L

IgM

0.45 g/L

4.Inflammatory markers

C-reactive protein

14 mg/L

Interleukin 6

51.8 pg/L

6.complications

infection

yes

anastomotic leakage

7.Discharge summary

hospitalization costs

63549 yuan

hospital stays

21 Day