当前位置:公众访问 >页面
简体中文 / English
1.Screening
1.1.Inclusion Criteria

women of childbearing age using contraceptives

no limitations regarding gender or ethnicity

男性

patients diagnosed with the disease for at least 1 year, which affected sleep quality during the onset period,

moderate-to-severe PAR patients aged between 18 to 65 years, and testing positive with a skin prick test for house dust mite (ALK reagent), according to Allergic Rhinitis and its Impact on Asthma (ARIA,2008)

1.2.Exclusion Criteria

patients unable to comply with follow-up requests

patients with cerebrovascular, lung, liver, kidney or cardiovascular diseases

patients with irregular lifestyle

long-term users of corticosteroids or immunosuppressive agents

patients with nasal polyps, sinusitis, or obvious deviated nasal septum

pregnant or breastfeeding women

patients aged younger than 18 or older than 65

2.2.RQLQ

Behavior

Emotional function

Sleep

Non-nasal/eye

Emotional function

Sleep

2.Baseline
2.1.Symptoms score

Nasal Itch

Rhinorrhoea

nasal obstruction

nasal obstruction

Sneezing

Rhinorrhoea

Nasal Itch

Sneezing

2.2.

Non-nasal/eye

Emotional function

Behavior

Sleep

3.After 2nd of the treatment
3.1.

Nasal Itch

TNSS

Rhinorrhoea

Sneezing

nasal obstruction

3.2.

Behavior

Emotional function

Sleep

Non-nasal/eye

4.At the end of the treatment
4.1.

Nasal Itch

Rhinorrhoea

Sneezing

nasal obstruction

4.2.

Sleep

Emotional function

Behavior

Non-nasal/eye

5.Follow-up week 8
5.1.

nasal obstruction

Rhinorrhoea

Nasal Itch

Sneezing

5.2.

Behavior

Sleep

Non-nasal/eye

Emotional function

6.Follow-up week 12(After 8 weeks of the treatment)
6.1.

Sneezing

Nasal Itch

nasal obstruction

Rhinorrhoea

6.2.

Emotional function

Sleep

Behavior

Non-nasal/eye

7.Follow-up 16 week(After 12 weeks of the treatment)
7.1.

nasal obstruction

Rhinorrhoea

Nasal Itch

Sneezing

7.2.

Sleep

Behavior

Emotional function

Non-nasal/eye

8.Management system of participants
9.Speciman management system
10.Data management system
11.ADR/ADE management system
12.Madicine management system
13.Instruments management system
15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size